HIGH PRESSURE PROCESSING (HPP) is a non-thermal pasteurization method that can be applied to cosmetic and pharmaceutical products.
HPP main advantages in the pharma-cosmetic sector are:
- Greater safety without heat treatment: Reduces drastically the overall spoiling and pathogenic flora.
- Extends shelf life maintaining functional properties and activity of thermo sensitive molecules (vitamins, proteins...)
- Vaccine production: inactivation of pathogens (bacteria, virus) whilst saving its antigen response intact.
- Production of new formulas: hypoallergenic, lower preservatives...
- Disaggregation and controlled re-naturalization of proteins of therapeutic interest.
- HPP can be used to process a wide range of products: liquid and semisolid, emulsions, gels, etc. either middle products or the final product already in its commercial package.
- Aertsen, A.; Meersman, F.; Hendrickx, M. E. G.; Vogel, R. F. & Michiels, C. W. Biotechnology under high pressure: applications and implications. Trends in Biotechnology 2009, 27(7), 434–441.
- Masson, P.; Tonello, C. & Balny, C. High pressure biotechnology in medecine and pharmaceutical science. Journal of Biomedicine and Biotechnology 2001, 1(2), 85–88.
- Qoronfleh, M. W.; Hesterberg, L. K. & Seefeldt, M. B. Confronting high-throughput protein refolding using high pressure and solution screens. Protein Expression and Purification 2007, 55(2), 209–224.